This decrease in viscosity of the mucous secretion allows for more efficient clearance. When acetylcysteine is used as a mucolytic in the respiratory tree, GI tract, or uterus, the mechanism of action is through disruption of the disulfide bonds in mucin. It may also be nebulized, used topically on the eye, or instilled in the rectum or uterus. It has a number of uses in veterinary medicine, including the treatment of acetaminophen toxicity of dogs and cats, intra-uterine treatment in mares, meconium impaction in foals, and as an adjunct in the treatment of Keratoconjunctivitis Sicca (KCS) and corneal ulcers.Īcetylcysteine may be administered intravenously or orally in the treatment of acetaminophen poisoning. Acetylcysteine is a mucolytic that is used in human medicine to decrease the viscosity of respiratory secretion, particularly in patients with cystic fibrosis.
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